Search results for "Anterior Eye Segment"

showing 10 items of 17 documents

Long-Term in vivo Evaluation of Orthotypical and Heterotypical Bioengineered Human Corneas.

2020

Purpose: Human cornea substitutes generated by tissue engineering currently require limbal stem cells for the generation of orthotypical epithelial cell cultures. We recently reported that bioengineered corneas can be fabricated in vitro from a heterotypical source obtained from Wharton’s jelly in the human umbilical cord (HWJSC). Methods: Here, we generated a partial thickness cornea model based on plastic compression nanostructured fibrin-agarose biomaterials with cornea epithelial cells on top, as an orthotypical model (HOC), or with HWJSC, as a heterotypical model (HHC), and determined their potential in vivo usefulness by implantation in an animal model. Results: No major side effects …

0301 basic medicinePathology02 engineering and technology:Chemicals and Drugs::Carbohydrates::Polysaccharides::Sepharose [Medical Subject Headings]Umbilical cord:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans [Medical Subject Headings]heterotypical human corneaTissue engineering:Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Lagomorpha::Rabbits [Medical Subject Headings]Cornea:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Optical Imaging::Tomography Optical::Tomography Optical Coherence [Medical Subject Headings]:Organisms::Eukaryota::Animals [Medical Subject Headings]:Technology and Food and Beverages::Technology Industry and Agriculture::Manufactured Materials::Biomedical and Dental Materials::Biocompatible Materials [Medical Subject Headings]Slit lamp021001 nanoscience & nanotechnologymedicine.anatomical_structure:Anatomy::Sense Organs::Eye::Anterior Eye Segment::Cornea [Medical Subject Headings]tissue engineeringStem cell0210 nano-technologyBiotechnology:Chemicals and Drugs::Amino Acids Peptides and Proteins::Proteins::Blood Proteins::Fibrin [Medical Subject Headings]medicine.medical_specialtyHistologyStromal celllcsh:BiotechnologyBiomedical EngineeringCélulas madre mesenquimatosasBioengineering:Anatomy::Embryonic Structures::Fetus::Umbilical Cord [Medical Subject Headings]:Analytical Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Models Animal [Medical Subject Headings]03 medical and health sciencesIn vivolcsh:TP248.13-248.65medicine:Anatomy::Cells::Connective Tissue Cells::Stromal Cells::Mesenchymal Stromal Cells [Medical Subject Headings]:Technology and Food and Beverages::Technology Industry and Agriculture::Engineering::Bioengineering::Cell Engineering::Tissue Engineering [Medical Subject Headings]Wharton’s jelly stem cellsbioengineered corneabusiness.industryTissue engineringeye diseasesEpitheliumCórnea:Anatomy::Cells::Epithelial Cells [Medical Subject Headings]:Anatomy::Tissues::Connective Tissue::Wharton Jelly [Medical Subject Headings]030104 developmental biologyIngeniería de tejidossense organsbusinessartificial cornea
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Preoperative simulation of postoperative iris-fixated phakic intraocular lens position and simulation of aging using high-resolution Scheimpflug imag…

2006

To increase postoperative safety after implantation of iris-fixated phakic intraocular lenses (pIOLs), optimal preoperative evaluation and patient selection is mandatory. We present a new software tool in a high-resolution Scheimpflug imaging device that precisely simulates the postoperative position of an iris-fixated pIOL and also simulates the effect of aging on the pIOL's position.

AdultAgingmedicine.medical_specialtygenetic structuresmedicine.medical_treatmentSoftware toolScheimpflug principleIrisHigh resolutionIntraocular lensPhakic intraocular lensPreoperative careImaging Three-DimensionalLens Implantation IntraocularAnterior Eye SegmentOphthalmologyLens CrystallinePreoperative CaremedicineHumansComputer SimulationPostoperative PeriodIris (anatomy)Lens crystallinebusiness.industryeye diseasesSensory SystemsOphthalmologymedicine.anatomical_structureFemaleSurgerysense organsbusinessJournal of Cataract and Refractive Surgery
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Effect of contact lenses on ocular biometric measurements based on swept-source optical coherence tomography

2019

ABSTRACT Purpose: To determine the reliability of swept- source optical coherence tomography in cases in which soft contact lenses cannot be removed when acquiring biometric measurements. Methods: Eight subjects were included and only one eye per participant was analyzed. Each eye was measured six times by swept-source optical coherence tomography with the IOLMaster 700 instrument (Carl Zeiss Meditec, Jena, Germany). Axial length, central corneal thickness, anterior chamber depth, lens thickness, and keratometric measurements were evaluated for the naked eye and while wearing soft contact lenses of three different powers (-1.5, -3.0, and +2.0 D). Results: There were statistically significan…

AdultBiometryMaterials sciencegenetic structuresContact LensesTomography optical coherenceStatistics Nonparametriclaw.invention03 medical and health sciences0302 clinical medicineOpticslcsh:OphthalmologyOptical coherence tomographyLens thicknessAnterior Eye SegmentReference ValueslawmedicineHumansContact lensesAnalysis of VarianceCross-Over Studiesmedicine.diagnostic_testbusiness.industryReproducibility of ResultsGeneral MedicineAxial lengtheye diseasesContact lensLens (optics)Axial Length EyeOphthalmologylcsh:RE1-994Reference values030221 ophthalmology & optometrysense organsTomographybusinessTomography Optical CoherenceArquivos Brasileiros de Oftalmologia
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Curvature of iris profile in spectral domain optical coherence tomography and dependency to refraction, age and pupil size - the MIPH Eye&Health …

2016

Purpose Optical coherence tomography (OCT) of the anterior segment allows quantitative analysis of the geometry of the iris. We performed spectral domain OCT examinations in healthy emmetropic, hyperopic and myopic subjects to investigate iris curvature and its associations. Methods In a cross-sectional study, out of 4617 eyes (2309 subjects) those with refractive errors of +3 dioptres were identified by objective refraction. The iris was examined using the anterior segment mode of a spectral domain 3D OCT-2000 (Topcon Inc., Japan) in the temporal meridian, and OCT scans were investigated with respect to presence and amount of convex and concave iris configuration. Ninety-three eyes of 50 s…

AdultMaleAdolescentgenetic structuresGonioscopyIrisEmmetropiaSpectral domainRefraction OcularCurvatureYoung Adult03 medical and health sciences0302 clinical medicineOptical coherence tomographyAnterior Eye SegmentGermanyEye healthHumansMedicineIntraocular PressureAgedmedicine.diagnostic_testbusiness.industryIncidenceAge FactorsPupil sizePupilGeneral MedicineMiddle AgedRefractive ErrorsRefractioneye diseasesOphthalmologyCross-Sectional StudiesMeridian (perimetry visual field)030221 ophthalmology & optometryOptometryFemalesense organsbusinessTomography Optical Coherence030217 neurology & neurosurgeryActa Ophthalmologica
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Evaluation of the anterior chamber angle in keratoconus and normal subjects.

2015

To evaluate the anterior chamber angle in keratoconus eyes by use of the Visante™ OCT and Orbscan™ II.Anterior chamber angle was measured with the Visante™ OCT and Orbscan™ II in 52 subjects, 26 KC subjects and 26 age and control subjects.When comparing the nasal and temporal angles obtained with the two techniques no correlation was found (R(2) always below 0.01) in either the control subjects or in the KC subjects. Despite this, there was an overall statistically significant difference in mean anterior chamber angles (p0.001) between Visante™ OCT and Orbscan™ II. There was no statistical difference (p0.05) between nasal and temporal anterior chamber angles when comparing controls and KC s…

AdultMaleKeratoconusmedicine.medical_specialtyKeratoconusSensitivity and SpecificityAnterior chamber angleAnterior Eye SegmentReference ValuesOphthalmologymedicineHumansOrbscan iiSlit Lampbusiness.industrySignificant differenceCorneal TopographyReproducibility of ResultsGeneral Medicinemedicine.diseaseControl subjectsOphthalmologyOptometryFemalebusinessTomography Optical CoherenceOptometryContact lensanterior eye : the journal of the British Contact Lens Association
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Five-year functional outcomes and vault of -20 diopter myopic phakic intraocular lens implantation.

2015

Purpose To evaluate refractive and visual outcomes and complications associated with phakic intraocular lens (pIOL) implantation to correct high myopia. Settings Fernandez-Vega Ophthalmological Institute, Oviedo, Spain. Design Retrospective observational case series. Methods Uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA), refraction, vault, and adverse effects were evaluated after 5 years with Visian ICMV4 pIOL. Results Mean spherical equivalent (SE) dropped from −18.32 ± 2.37 diopters (D) preoperatively to −0.88 ± 0.52D 5 years postoperatively; 61% of eyes were within ±0.75 D of the target. The mean Snellen decimal CDVA and UDVA were 0.73 ± 0.23 and 0…

AdultMalePhakic Intraocular LensesVisual acuityAnterior subcapsular cataractDistance visual acuityBiometrygenetic structuresmedicine.medical_treatmentVisual AcuityPhakic intraocular lensRefraction OcularPostoperative ComplicationsLens Implantation IntraocularAnterior Eye SegmentmedicineMyopiaHumansDioptreRetrospective StudiesEfficacy indexbusiness.industryHigh myopiaCataract surgeryeye diseasesSensory SystemsOphthalmologyOptometrySurgeryFemalesense organsmedicine.symptombusinessTomography Optical CoherenceFollow-Up StudiesJournal of cataract and refractive surgery
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Scheimpflug biometry of the anterior segment after implantation of foldable iris-fixated lenses.

2006

ABSTRACT PURPOSE: To evaluate intraocular dimensions of the anterior segment of myopic phakic eyes after implantation of foldable iris-fixated lenses. METHODS: Seventeen myopic eyes that received a foldable iris-fixated phakic intraocular lens (PIOL) were assessed. Distances between the cornea and the IOLoptic edge and between the IOL optic and the crystalline lens were evaluated using Scheimpf lug photography 3 months postoperatively. RESULTS: The average postoperative distance between the central corneal endothelium and the anterior surface of the IOL was 2.01±0.26 mm. The distance between the corneal endothelium and the peripheral edge of the IOL averaged 1.32±0.18 mm at the 12 o'clock p…

AdultMalemedicine.medical_specialtyCorneal endotheliumBiometrygenetic structuresScheimpflug principleIrisAnterior surfacePhakic intraocular lensRefraction Ocularlaw.inventionLens Implantation IntraocularlawAnterior Eye SegmentCorneaOphthalmologyLens CrystallinemedicineMyopiaPhotographyHumansIris (anatomy)Retrospective StudiesLenses Intraocularbusiness.industrySuture Techniqueseye diseasesLens (optics)Ophthalmologymedicine.anatomical_structureSurgeryFemalesense organsbusinessFollow-Up StudiesJournal of refractive surgery (Thorofare, N.J. : 1995)
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Avaliação por OCT in vivo do comprimentos axiais centrais do segmento anterior

2017

ABSTRACT Purpose: To assess changes in anatomic structures in the anterior eye segment in terms of axial lengths with accommodation via optical coherence tomography. Methods: In this observational study, 25 eyes of 25 healthy adults were examined using the Visante® omni optical coherence tomography system. Central corneal thickness, anterior chamber depth, central lens thickness, and anterior segment length were assessed. The evaluated parameters were obtained with accommodation using different stimulus vergences, namely 0.0, -1.0, -2.0, and -3.0 D. Variation of these parameters was compared among different levels of accommodation. Results: Central corneal thickness was not altered at any s…

AdultMalemedicine.medical_specialtySegmento anterior do olhoPosterior poleOcular physiologyYoung AdultOcular accommodationOptical coherence tomographyLens thicknesslcsh:OphthalmologyAnterior Eye SegmentOphthalmologymedicineHumansmedicine.diagnostic_testOptical coherence tomographybusiness.industrySegment lengthAccommodation OcularGeneral MedicineMiddle AgedAnterior eye segmentAnterior Eye SegmentOphthalmologylcsh:RE1-994Acomodação ocularTomografia de coerência ópticaFemaleTomographysense organsbusinessAccommodationTomography Optical Coherence
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Behaviour of the phakic iris-claw intraocular lens (Artisan /Verisyse) during accommodation: an optical coherence biometry study.

2007

Purpose To evaluate variations in the position of the phakic iris claw lens (Artisan®, Verisyse®) and the natural crystalline lens during the accommodation process. Methods We measured changes in position of the iris claw lens and the crystalline lens during the accommodation using optical coherence biometry (AC Master®/Carl Zeiss Meditec, Germany) in 17 patients (28 eyes) with a phakic iris claw lens implanted for high myopia and/or myopic astigmatism. Accommodative effort was obtained using an internal optical target within the measuring device. Results There was a forward shift of the phakic iris claw lens with a mean of 70 μm (8–178 μm) of the optical path length (OPL). At the same time…

Adultmedicine.medical_specialtyPhakic Intraocular LensesMaterials scienceBiometrymedicine.medical_treatmentIrisIntraocular lensRefraction OcularMyopic astigmatism03 medical and health sciences0302 clinical medicineOpticsLens Implantation IntraocularAnterior Eye SegmentOphthalmologyLens CrystallinemedicineMyopiaHumansIris clawOptical path lengthbusiness.industryHigh myopiaAccommodation OcularAstigmatismGeneral MedicineMiddle AgedOphthalmologymedicine.anatomical_structureLens (anatomy)030221 ophthalmology & optometrybusinessAccommodation030217 neurology & neurosurgeryTomography Optical CoherenceCoherence (physics)Follow-Up StudiesEuropean journal of ophthalmology
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Axial Length and Anterior Segment Alterations in Former Preterm Infants and Full-Term Neonates Analyzed With Scheimpflug Imaging.

2017

Purpose To compare the axial length and anterior segment alterations in preterm infants with and without retinopathy of prematurity with those of full-term infants. Methods The Wiesbaden Prematurity Study investigated 503 participants of former gestational age ≤32 weeks and gestational age ≥37 weeks now being aged 4 to 10 years. This study included 485 participants in the prospective controlled cross-sectional, hospital-based study with successful Pentacam Scheimpflug imaging. Anterior segment parameters, axial length measurements, and associated factors were analyzed. Results Corneal thickness did not differ between former preterm and full-term infants. Significant differences were found b…

Diagnostic ImagingMalePediatricsmedicine.medical_specialtyCorneal PachymetryTerm BirthBirth weightVisual AcuityGestational AgeAstigmatismRefraction Ocular03 medical and health sciences0302 clinical medicineAnterior Eye SegmentMedicineBirth WeightHumansProspective StudiesCorneal pachymetryChildFull Termmedicine.diagnostic_testbusiness.industryGestational ageRetinopathy of prematurityInfant Low Birth Weightmedicine.diseaseRefractive ErrorsOphthalmologyLow birth weightAxial Length EyeCross-Sectional Studies030221 ophthalmology & optometryTerm BirthFemalemedicine.symptombusiness030217 neurology & neurosurgeryInfant PrematureCornea
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